Every day, your body is exposed to toxins from food, air pollution, household products, medications, alcohol, pesticides, and normal metabolic processes.
While the body has sophisticated detoxification systems designed to process and remove these substances, genetic differences can influence how efficiently these pathways work.
For some people, reduced detoxification capacity may contribute to symptoms such as fatigue, headaches, brain fog, skin issues, digestive discomfort, chemical sensitivities, poor stress resilience, or difficulty recovering from illness.
The DNA Detoxification Panel helps uncover how your genes influence the body’s ability to process, neutralise, and eliminate toxins. It may help explain why some individuals appear more sensitive to environmental exposures, medications, alcohol, or oxidative stress than others.
The report provides personalised insights that can help guide nutrition, lifestyle, and supplement decisions, reducing guesswork and supporting a more targeted approach to health optimisation. If you’d like guidance from an expert practitioner consider booking a consultation with our Functional Medicine team for Nutrigenomics.
Your report includes:
Your DNA sample will be anonymised before processing at the UK lab. DNA samples and genotyping data are permanently destroyed after strict retention periods. For more information please read our Privacy Policy.
This test may be particularly useful for individuals looking to understand how their body manages toxins, supports liver function, and responds to environmental exposures.
Adults and children who:
Detoxification Enzymes: Assesses pathways involved in the first stage of detoxification, where the body begins breaking down toxins, medications, hormones, and environmental chemicals before they can be safely removed. Includes: CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4.
Alcohol Metabolism: Assesses pathways involved in how efficiently your body processes alcohol and the by-products created during alcohol breakdown. Includes: ADH1B, ADH1C, ALDH2.
Pesticide Sensitivity: Assesses pathways involved in the body’s ability to process and eliminate pesticide exposure from food and the environment. Includes: PON1.
Oxidative Stress & Antioxidant Protection: Assesses pathways that help protect cells from oxidative stress generated during detoxification and everyday environmental exposures. Includes: SOD2, GPX1, NQO1.
Glucuronidation: Assesses pathways involved in packaging toxins, hormones, and waste products so they can be safely removed from the body. Includes: UGT1A1, UGT1A6.
Methylation Support: Assesses pathways involved in detoxification, hormone balance, neurotransmitter activity, immune resilience, and cellular repair. Includes: COMT, TPMT.
Sulphonation: Assesses pathways involved in processing hormones, medications, food compounds, and environmental toxins for elimination. Includes: SULT1A1, SULT1E1, SULT2A1.
Acetylation: Assesses pathways involved in how the body metabolises certain drugs, pollutants, and environmental compounds. Includes: NAT1, NAT2.
Glutathione Production: Assesses pathways involved in producing glutathione, one of the body’s most important antioxidants for detoxification, cellular protection, and immune health. Includes: GSTM1, GSTP1, GSTT1.
Cellular Transport & Detoxification Capacity: Assesses pathways involved in moving substances into and out of cells, influencing how efficiently toxins and other compounds can be transported and eliminated. Includes: ABCB1.
You should:
You shouldn’t:
The test is designed to be simple and non-invasive.
However, please make sure to follow the instructions and complete the documentation to ensure your sample can be analysed. Samples that aren’t suitable will need to be recollected at an additional cost.
At-home cheek swab DNA sample.
You’ll be invited to join our online portal, Practice Better, where you can securely access your results and communications.
Once your sample arrives at the laboratory, analysis typically takes around 14 working days. Once available, your report will be shared securely through the portal for download and future reference. You may also choose to book an optional consultation with a qualified practitioner at this stage.
See our Privacy Policy for information about how your data will be processed by The Forbes Clinic and our third party testing suppliers.
Turnaround times vary depending on the test. We aim to process and submit your order to our provider within 2 working days. Test kits are promptly dispatched, and most samples can be collected and returned as soon as you're ready. Some tests may have specific requirements, such as timing around menstruation or return days. These details can be found under "How do I prepare for the test?" and in your kit. Estimated turnaround times refer to how long it takes to analyse your sample once it’s received at the laboratory.
All at-home test kits include clear instructions for sample collection and return, along with necessary packaging. Some tests require you to return the sample on specific days or immediately after collection. Most kits include pre-paid return labels, but some may require you to arrange a prepaid courier collection. Review the instructions carefully before collecting your sample and refer to the contact details in your kit for any questions.
Your kit will come with full instructions and some include video guides. We can support with queries and we encourage you to contact us using the link below before collecting your sample to ensure it can be effectively analysed.
We offer functional testing with and without practitioner interpretation. You can filter tests by consultation on the Functional Testing page. Certain tests, especially those involving clinically significant biomarkers, are only available with interpretation, and some require interpretation by an Integrative Medicine Doctor. We’ll ensure you’re seen by the right practitioner when your results are in. You can purchase a consultation later if you choose standalone testing, but we offer preferential rates for booking upfront.
We provide functional testing to help you make informed health decisions but do not offer medical advice, diagnosis, or treatment. Results are interpreted through a nutritional, lifestyle, and functional medicine perspective, and it is your responsibility to seek further evaluation, diagnosis or treatment from your primary healthcare provider.
Your digital results report will include indicators of how your specific results differ or align with ‘optimal’ ranges in functional medicine. Some reports include an element of written interpretation. If you’ve purchased a consultation we’ll explain your results and interpret them from a nutritional, lifestyle and functional medicine perspective. We may offer suggestions about how Integrative or Functional Medicine can help and can refer you for full consultation or Integrative Health Assessment with a relevant practitioner if desired. If your test includes a clinically significant biomarker and your result is abnormal, we’ll direct you to consult your primary healthcare provider. If you haven’t purchased a consultation and you’re concerned about your results, you’ll be able to opt-in at this stage.
All third party testing providers are GDPR compliant and adhere strictly to regulatory and industry standards for processing sensitive health data in line with their own Privacy Policies (available on the product page). Results are shared with The Forbes Clinic via each provider's secure online portal and with you via our secure online portal, Practice Better. The Forbes Clinic handles your personal data with care and sensitivity in line with GDPR and according to the terms laid out in our Privacy Policy. Please refer to the privacy policy for more information about exercising your rights under GDPR.
By purchasing testing you acknowledge you have read, understood and agree to our Terms and Conditions